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Effect of HstN and HstP on peroxidase activity in SH-SY5Y-APP695 cells. Peroxidase activity in SH-SY5Y-APP695 cells: (A) incubated for 24 h with HstN, with PC as control, and (B) incubated for 24 h with HstP, with ethanol as control. Respective mean values ± SD are shown, N = 10. Significance was determined by unpaired Student’s t-test. **** p < 0.0001. HstN, hesperetin nanocrystal; HstP, hesperetin in pure form; PC, PlantaCare; EtOH, ethanol.
