Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Probability of target attainment (PTA) for tedizolid (200 mg q24h) and linezolid (600 mg q12h).
| Probability of Target Attainment, PTA (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC (mg/L) | ||||||||||
| PK/PD Target | 0.06 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | |
| Tedizolid | fAUC24/MIC ≥ 3 | 100 | 100 | 100 | 97 | 55 | 11 | 1 | 0 | 0 |
| Linezolid | fAUC24/MIC ≥ 80 | 100 | 100 | 100 | 100 | 97 | 62 | 19 | 4 | 0 |
In grey PTA values ≥ 90% (high probability of success).
