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. 2021 Jun 22;10(7):755. doi: 10.3390/antibiotics10070755

Table 5.

Probability of success (expressed as CFR or cumulative fraction of response) of tedizolid and linezolid for staphylococci.

Microorganism/Study Resistance Phenotype Probability of Success (CFR, %)
Tedizolid Linezolid
S. aureus
Sahm et al. [22] 99 69
Zurenko et al. [23] 99 67
Rodríguez-Avial et al. [24] LR 97 3
Pfaller et al. [25] 100 n.c.
MRSA
Sahm et al. [22] 71
Barber et al. [26] hVISA 99 n.c.
VISA 100 n.c.
DNS 100 n.c.
LR 80 n.c.
Peñuelas et al. [27] MRSA 99 75
MLRSA 62 n.c.
Pfaller et al. [25] 100 n.c.
CoNS
Sahm et al. [22] 94 n.c.
Zurenko [23] 99 93
Rodríguez-Avial et al. [24] LR 20 0
Pfaller et al. [25] 100 n.c.

DNS: daptomycin-non-susceptible; LR: linezolid resistant; hVISA: heterogenous vancomycin intermediate; VISA: vancomycin intermediate; MRSA: methicillin-resistant S. aureus, MLRSA: methicillin- and linezolid-resistant S. aureus. n.c.: not calculated due to lack of MIC data.