Table 5.
Microorganism/Study | Resistance Phenotype | Probability of Success (CFR, %) | |
---|---|---|---|
Tedizolid | Linezolid | ||
S. aureus | |||
Sahm et al. [22] | 99 | 69 | |
Zurenko et al. [23] | 99 | 67 | |
Rodríguez-Avial et al. [24] | LR | 97 | 3 |
Pfaller et al. [25] | 100 | n.c. | |
MRSA | |||
Sahm et al. [22] | 71 | ||
Barber et al. [26] | hVISA | 99 | n.c. |
VISA | 100 | n.c. | |
DNS | 100 | n.c. | |
LR | 80 | n.c. | |
Peñuelas et al. [27] | MRSA | 99 | 75 |
MLRSA | 62 | n.c. | |
Pfaller et al. [25] | 100 | n.c. | |
CoNS | |||
Sahm et al. [22] | 94 | n.c. | |
Zurenko [23] | 99 | 93 | |
Rodríguez-Avial et al. [24] | LR | 20 | 0 |
Pfaller et al. [25] | 100 | n.c. |
DNS: daptomycin-non-susceptible; LR: linezolid resistant; hVISA: heterogenous vancomycin intermediate; VISA: vancomycin intermediate; MRSA: methicillin-resistant S. aureus, MLRSA: methicillin- and linezolid-resistant S. aureus. n.c.: not calculated due to lack of MIC data.