Figure 3.

Effect of oral administration of nutraceuticals on retinal redox status in rd10 mice at PD18. (a) Values of the antioxidant markers TAC, and activities of superoxide dismutase (SOD) 1 or cytosolic (SOD1), 2 or mitochondrial (SOD2), catalase (CAT) and glutathione peroxidase (GPx), and (b) values of the oxidant markers thiobarbituric acid reactive substances (TBARS, indicator of lipid peroxidation) and protein carbonyl groups (CAR, indicator of protein oxidation) from control mice (C), untreated rd10 mice and NUT-treated rd10 mice. rd10 mice were treated with NUT from PD9 to PD18. Data were presented as mean ± S.E.M. from at least eight retinas for each experimental group. Statistical differences between groups (p < 0.05) were shown * p < 0.05; ** p < 0.01; *** p < 0.001 using one-way ANOVA or Kruskal–Wallis test and post hoc Tukey’s or Dunn´s multiple comparisons tests.