Table 2.
Gene expression of inflammatory molecules in retinas from rd10 mice with or without oral administration of nutraceuticals.
| Gene | C Relative Expression (Mean ± SEM) |
rd10 Relative Expression (Mean ± SEM) |
rd10 + NUT Relative Expression (Mean ± SEM) |
|---|---|---|---|
| TNFα | 1.0 ± 0.0 | 40.8 ± 8.0 *** | 5.8 ± 1.4 * |
| TNFR1 | 1.0 ± 0.1 | 2.3 ± 0.4 * | 0.9 ± 0.2 bbb |
| IL-6 | 1.0 ± 0.0 | 7.8 ± 2.0 ** | 2.5 ± 0.6 bb |
| IL-1β | 1.0 ± 0.0 | 17.0 ± 3.0 *** | 3.6 ± 0.8 bb |
| IL-18 | 1.0 ± 0.1 | 0.4 ± 0.1 * | 0.1 ± 0.0 *** |
| GFAP | 1.0 ± 0.0 | 8.3 ± 1.0 *** | 2.6 ± 0.5 **b |
Note: Gene expression (relative expression) in each group. Differences between untreated rd10 (rd10) mice and control (C) or NUT-treated rd10 mice (rd10 + NUT) were analyzed using Kruskal–Wallis test and post hoc Dunn´s multiple comparisons tests. C, control. * p < 0.05; ** p < 0.01; *** p < 0.001 for differences between control and rd10 mice; and b p < 0.05; bb p < 0.01; bbb p < 0.001 for differences between rd10 and rd10 + NUT mice.