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. 2021 Jul 16;10(7):868. doi: 10.3390/antibiotics10070868

Table 6.

Time-series regression analysis of correlations between meropenem and Ciprofloxacin resistance in Klebsiella and antibiotic consumption.

Outcome Used R Sq. Predictors in the Model Coefficient 95% Confidence
Interval
p
Resistance to Meropenem 0.627 Consumption of Imipenem 1 month before 0.0243 [−0.0043, 0.0529] 0.078
Consumption of Meropenem 1 month before −0.0016 [−0.0057, 0.0025] 0.341
Resistance to Meropenem 0.753 Consumption of Imipenem 2 months before 0.0075 [0.0011, 0.0130] 0.032 *
Consumption of Meropenem 2 months before −0.0042 [−0.0077, 0.0081] 0.027
Resistance to Ciprofloxacin 0.753 Consumption of Imipenem 2 months before 0.0010 [0.0007, 0.0014] <0.001 *
Consumption of Meropenem 2 months before −0.0002 [−0.0001, 0.0010] 0.094
Consumption of Ciprofloxacin 2 months before 0.0004 [0.0001, 0.0007] 0.0047 *
Resistance to Ciprofloxacin 0.537 Consumption of Imipenem 3 months before 0.0064 [0.0004, 0.0009] <0.001
Consumption of Meropenem 3 months before 0.0001 [−0.0002, 0.0004] 0.571
Consumption of Ciprofloxacin 3 months before −0.0001 [−0.0004, 0.0001] 0.330

* p < 0.05.