Table 1.
MIC, MIC50, and MIC90 for COL, MEM, and TGC as collected from single MIC testing by broth microdilution for 50 isolates.
| Antimicrobial | MIC Range (mg/L) | MIC50 (mg/L) | MIC90 (mg/L) | Median Fold-Reduction |
|---|---|---|---|---|
| COL | 0.5–256 | 4 | 8 | |
| MEM | 8–128 | 32 | 128 | |
| TGC | 0.25–8 | 4 | 4 | |
| MEM+COL | 1–64 | 16 | 32 | 2 |
| TGC+COL | 0.25–8 | 2 | 4 | 2 |
MIC, minimum inhibitory concentration; COL, colistin; MEM, meropenem; TGC, tigecycline; MEM+COL, MEM in the presence of COL at 0.5 × MIC or biological free peak concentration; TGC+COL, TGC in the presence of COL at 0.5 × MIC or biological free peak concentration.