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CYP-dependent metabolic depletion of 5 μM 6d (red line, three time points, at 0, 30, and 60 min) and 6h (black line, six time points, at 0, 5, 15, 30, 45, and 60 min) in HLM preparation. Results are presented graphically as a percentage of compound recovery (100% at time 0 min) as a function of incubation time. Data are presented as mean ± SEM, of three different experiments.
