Skip to main content
. Author manuscript; available in PMC: 2022 Jul 22.
Published in final edited form as: J Med Chem. 2021 Jul 12;64(14):9960–9988. doi: 10.1021/acs.jmedchem.1c00184

Figure 4.

Figure 4.

Stereoview of a Polder omit map of the zfHDAC6/(S)-6h complex (PDB 6V79; contoured at 2.5 σ). The Zn2+-bound water molecule is contoured at 3.5 σ. Atoms are color-coded as follows: C = light blue (zfHDAC6 monomer A), light gray (zfHDAC6 monomer B), or wheat (inhibitor), N = blue, O = red, Zn2+ = gray sphere, and Zn2+-bound water molecule = small red sphere. Metal coordination and hydrogen bond interactions are indicated by solid and dashed black lines, respectively.