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Docked poses of (S)-(−)-6h (light blue sticks) into HDAC1 (PDB ID 4BKX; panel A) and HDAC6 (PDB ID 5EDU; panel B). The residues in the active sites are represented as lines and the proteins are represented as cartoons. Zn2+ is represented as a gray sphere. H-bonds are represented as black dotted lines, while the red stick represents the metal coordination bond.
