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. Author manuscript; available in PMC: 2022 Jul 22.
Published in final edited form as: J Med Chem. 2021 Jul 12;64(14):9960–9988. doi: 10.1021/acs.jmedchem.1c00184

Table 3.

Solubility and chemical stability of compounds 6d and 6h.

Compound Solubility (μM) after 24 h Chemical Stability (%) after 24 h
pH = 3 pH = 7.4 pH = 3
6d 456 285 98
6h 459 97 89
TubA 244 231 nca
a

nc: not calculated