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. 2021 Jun 30;10(7):1064. doi: 10.3390/antiox10071064
AA arachidonic acid
ABC ATP-binding cassette
AC adenylyl cyclase
ACC acetyl-CoA carboxylase
ADRP adipose differentiation-related protein activator protein 1
AhR aryl hydrocarbon receptor
AICD APP intracellular domain
Akt protein kinase B (serine/threonine-specific protein kinase)
ALP alkaline phosphatase
AMPK 5′-adenosine monophosphate-activated protein kinase
ANS anthocyanidin synthase
AP1 activator protein 1
APP amyloid precursor protein
AR androgen receptor
ARE antioxidant responsive element
AT acetyltransferase
ATF2 activating transcription factor 2 ATP, adenosine triphosphate
BAD Bcl2-associated agonist of cell death
B.Ar bone area
BCA biochanin A
BMI body mass index
BMP2 bone morphogenetic protein 2
BV/TV bone volume/tissue volume
Ca2+ calcium ion
C/EBP CCAAT/enhancer-binding proteins
CaMK II calmodulin kinase II
cAMP cyclic adenosine monophosphate
C/EBP-α CCAAT/enhancer-binding protein-alpha
c-Fos cellular oncogene fos
C4H cinnamic acid 4-hydroxylae
CHI chalcone isomerase
CHR chalcone reductase
CHS chalcone synthase
4CL 4-coumarate-CoA ligase
COL1a1 transcription factor Sp7 (Osterix), alpha-1 type I collagen
COX-2 cyclooxygenase 2
CRE carbohydrate response element
CREBp cyclic AMP-responsive element-binding protein
CTF C-terminal fragment
CTSK cathepsin K
DFR dihydroxyflavonol reductase
DMID 7,2′-dihydroxy-4′-methoxy-isoflavanol dehydratase
DHD dihydrodaidzein
DR5 tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2
DZ daidzein
EGF epidermal growth factor
EGFR epidermal growth factor receptor
eNOS endothelial nitric oxide synthase
EPR endoplasmic reticulum
ER estrogen receptor
ERAα/β estrogen receptor A alpha/beta
ERα estrogen receptor alpha
ERβ estrogen receptor beta
ERK1/2 extracellular signal-regulated kinase 1 and 2
F3H flavanone 3-hydroxylase
FADD Fas-associated protein with death domain
FAS fatty acid synthetase
FASL (CD95L) FAS ligand
PARP poly(ADP-ribose)-polymerase
FBG fasting blood glucose
FFAs free fatty acids
FLS flavonol synthase
FNS flavone synthase
FNT formononetin
FOXO forkhead box transcription factor family O
G2′DT glycinol 2-dimethylallyltransferase
G4′DT glycinol 4-dimethylallyltransferase
G6Pase glucose-6-phosphatase
GC glycetin
GDNF glial cell line-derived neurotrophic factor
GFr growth factor receptor
GK glucokinase
GLS glyceollin synthase
GLUT4 glucose transporter type 4
GPX glutathione peroxidase
gp91 (NOX2) NADPH oxidase subunit
G or GS genistein
GSH glutathione (reduced form)
GSK3β glycogen synthase kinase 3 beta
GT glucosyltransferase
6-HD 6-hydroxydaidzein
8-HD 8-hydroxydaidzein
12′H isoflavone hydroxylase
HER2 human epidermal growth factor receptor 2
HI4′OMT 2,7,4′-trihydroxyisoflavanone 4′-O-methyltransferase
HID 2-hydroxyisoflavone dehydratase
2-HIS 2-hydroxyisoflavone synthase
HNF4α hepatocyte nuclear factor 4 alpha
HO-1 heme oxygenase 1
I2′H isoflavone 2-hydroxylase
ICAM-1 intracellular adhesion molecule 1
ICHG isoflavone conjugate-hydrolyzing β-glucosidase
IF isoflavone
IF7GT isoflavone-7-O-glucosyltransferase
IF7MaT isoflavone-7-O-glucoside-6″-O-malonyltransferase
IFH isoflavone hydroxylase
IFR isoflavone reductase
IFS isoflavone synthase
IκB inhibitory protein of κB family
IKK IκB kinase
IL-1 interleukin 1
IMT isoflavone malonyl transferase
iNOS inducible nitric oxide synthases
INSR insulin receptor
IRβ insulin receptor beta
IRS1/2 insulin receptor substrate-1 and 2
ISN1 inosine 5′-monophosphate (IMP)-specific 5′-nucleotidase
JAK2 Janus kinase 2
LAR flavan-3,4-diol reductase
LDL low-density lipoprotein
LOX lipoxygenase
LPS lipopolysaccharide
Maf musculoaponeurotic fibrosarcoma protein
MAPK mitogen-activated protein kinase
MEK mitogen-activated protein kinase kinase
MKK1/7 mitogen-activated protein kinase kinase 1 and 7
MMP matrix metalloproteinase
MT malonyltransferase
MCP1 monocyte chemoattractant protein 1
MDA malonaldehyde
MGO methylglyoxal
NAD+ nicotinamide adenine dinucleotide (oxidized form)
NADPH nicotinamide adenine dinucleotide phosphate (reduced form)
NFATc1 nuclear factor of activated T-cells cytoplasmic 1
NFIL3 nuclear factor interleukin-3-regulated protein
NF-κB nuclear factor-kappa B
NGF nerve growth factor
NIK NF-κB-inducing kinase
nNOS neuronal isoform of nitric oxide synthase
NO nitrix oxide
NOX NADPH oxidase
NOX4 NAPDH oxidase 4
NQO1 NAD(P)H quinone oxidoreductase 1
Nrf2 nuclear factor erythroid 2
OCN osteocalcin
OPG osteoprotegerin
PAL phenylalanine ammonia lyase
p-AMPK phosphorylated adenosine 5′-monophosphate-activated protein kinase
PARP poly(ADP-ribose)-polymerase
PDK1/2 3-phosphoinositide–dependent protein kinase 1 and 2
PEPCK phosphoenolpyruvate carboxykinase
p-ERK phosphorylated extracellular signal-regulated kinase
PG prostaglandin
PGC-1α peroxisome proliferator-activated receptor-gamma coactivator-1alpha
PGE2 prostaglandin E2
PGF2 prostaglandin F2
PI3K phosphatidylinositol 3-kinase
PIP2 phosphatidylinositol-4,5-biphosphate
PIP3 phosphatidylinositol-3,4,5-triphosphate
PKA protein kinase A (cAMP-dependent protein kinase)
PKC protein kinase C
PLA2 phospholipase A2
PPARα peroxisome proliferator-activated receptor-alpha
PPARγ peroxisome proliferator-activated receptors-gamma
PTS pterocarpan synthase
PYK pyruvate kinase
RANKL receptor activator of NF-κB ligand
RIP receptor-interacting protein
ROS reactive oxygen species
RUNX2 runt-related transcription factor 2
S1P and S2P site-specific protease 1 and 2
sAPP soluble APP
SCAP SREB cleavage-activating protein
SIRT1 sirtuin 1
SCD1 stearoyl-CoA desaturase 1
SGK1 serine/threonine-protein kinase
SMI structure model index
SOD superoxide dismutase
SREB sterol regulatory element binding
STAT1 signal transducer and activator of transcription 1
STEBp1 SET-binding protein 1
T3 triiodothyronine
T4 thyroxine
TAK1 transforming growth factor β-activated kinase
TAT1 signal transducer and activator of transcription 1
TBARs thiobarbituric acid reactive substances
Tb.N trabecular number
Tb.Pf trabecular pattern factor
Tb.Sp trabecular separation
Tb.Th trabecular thickness
TCF T cell factor
TG Triacylglycerol
TGF-α transforming growth factor-alpha
TNF tumor necrosis factor
TNF-α tumor necrosis factor-alpha
TNFR tumor necrosis factor receptor
TNFR1 TNF receptor-1
TORC2 target of rapamycin complex 2
TRADD TNF receptor-associated death domain
TRAF2 TNF receptor-associated factor 2
TRAIL TNF-related apoptosis-inducing ligand
TRAP tartrate-resistant acid phosphatase
Ub ubiquitination
UCP1 uncoupling protein 1
VR vestitone reductase
Wnt/β-catenin canonical Wnt pathway
XRE xenobiotic response element