| AA | arachidonic acid |
| ABC | ATP-binding cassette |
| AC | adenylyl cyclase |
| ACC | acetyl-CoA carboxylase |
| ADRP | adipose differentiation-related protein activator protein 1 |
| AhR | aryl hydrocarbon receptor |
| AICD | APP intracellular domain |
| Akt | protein kinase B (serine/threonine-specific protein kinase) |
| ALP | alkaline phosphatase |
| AMPK | 5′-adenosine monophosphate-activated protein kinase |
| ANS | anthocyanidin synthase |
| AP1 | activator protein 1 |
| APP | amyloid precursor protein |
| AR | androgen receptor |
| ARE | antioxidant responsive element |
| AT | acetyltransferase |
| ATF2 | activating transcription factor 2 ATP, adenosine triphosphate |
| BAD | Bcl2-associated agonist of cell death |
| B.Ar | bone area |
| BCA | biochanin A |
| BMI | body mass index |
| BMP2 | bone morphogenetic protein 2 |
| BV/TV | bone volume/tissue volume |
| Ca2+ | calcium ion |
| C/EBP | CCAAT/enhancer-binding proteins |
| CaMK II | calmodulin kinase II |
| cAMP | cyclic adenosine monophosphate |
| C/EBP-α | CCAAT/enhancer-binding protein-alpha |
| c-Fos | cellular oncogene fos |
| C4H | cinnamic acid 4-hydroxylae |
| CHI | chalcone isomerase |
| CHR | chalcone reductase |
| CHS | chalcone synthase |
| 4CL | 4-coumarate-CoA ligase |
| COL1a1 | transcription factor Sp7 (Osterix), alpha-1 type I collagen |
| COX-2 | cyclooxygenase 2 |
| CRE | carbohydrate response element |
| CREBp | cyclic AMP-responsive element-binding protein |
| CTF | C-terminal fragment |
| CTSK | cathepsin K |
| DFR | dihydroxyflavonol reductase |
| DMID | 7,2′-dihydroxy-4′-methoxy-isoflavanol dehydratase |
| DHD | dihydrodaidzein |
| DR5 | tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 |
| DZ | daidzein |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| eNOS | endothelial nitric oxide synthase |
| EPR | endoplasmic reticulum |
| ER | estrogen receptor |
| ERAα/β | estrogen receptor A alpha/beta |
| ERα | estrogen receptor alpha |
| ERβ | estrogen receptor beta |
| ERK1/2 | extracellular signal-regulated kinase 1 and 2 |
| F3H | flavanone 3-hydroxylase |
| FADD | Fas-associated protein with death domain |
| FAS | fatty acid synthetase |
| FASL (CD95L) | FAS ligand |
| PARP | poly(ADP-ribose)-polymerase |
| FBG | fasting blood glucose |
| FFAs | free fatty acids |
| FLS | flavonol synthase |
| FNS | flavone synthase |
| FNT | formononetin |
| FOXO | forkhead box transcription factor family O |
| G2′DT | glycinol 2-dimethylallyltransferase |
| G4′DT | glycinol 4-dimethylallyltransferase |
| G6Pase | glucose-6-phosphatase |
| GC | glycetin |
| GDNF | glial cell line-derived neurotrophic factor |
| GFr | growth factor receptor |
| GK | glucokinase |
| GLS | glyceollin synthase |
| GLUT4 | glucose transporter type 4 |
| GPX | glutathione peroxidase |
| gp91 (NOX2) | NADPH oxidase subunit |
| G or GS | genistein |
| GSH | glutathione (reduced form) |
| GSK3β | glycogen synthase kinase 3 beta |
| GT | glucosyltransferase |
| 6-HD | 6-hydroxydaidzein |
| 8-HD | 8-hydroxydaidzein |
| 12′H | isoflavone hydroxylase |
| HER2 | human epidermal growth factor receptor 2 |
| HI4′OMT | 2,7,4′-trihydroxyisoflavanone 4′-O-methyltransferase |
| HID | 2-hydroxyisoflavone dehydratase |
| 2-HIS | 2-hydroxyisoflavone synthase |
| HNF4α | hepatocyte nuclear factor 4 alpha |
| HO-1 | heme oxygenase 1 |
| I2′H | isoflavone 2-hydroxylase |
| ICAM-1 | intracellular adhesion molecule 1 |
| ICHG | isoflavone conjugate-hydrolyzing β-glucosidase |
| IF | isoflavone |
| IF7GT | isoflavone-7-O-glucosyltransferase |
| IF7MaT | isoflavone-7-O-glucoside-6″-O-malonyltransferase |
| IFH | isoflavone hydroxylase |
| IFR | isoflavone reductase |
| IFS | isoflavone synthase |
| IκB | inhibitory protein of κB family |
| IKK | IκB kinase |
| IL-1 | interleukin 1 |
| IMT | isoflavone malonyl transferase |
| iNOS | inducible nitric oxide synthases |
| INSR | insulin receptor |
| IRβ | insulin receptor beta |
| IRS1/2 | insulin receptor substrate-1 and 2 |
| ISN1 | inosine 5′-monophosphate (IMP)-specific 5′-nucleotidase |
| JAK2 | Janus kinase 2 |
| LAR | flavan-3,4-diol reductase |
| LDL | low-density lipoprotein |
| LOX | lipoxygenase |
| LPS | lipopolysaccharide |
| Maf | musculoaponeurotic fibrosarcoma protein |
| MAPK | mitogen-activated protein kinase |
| MEK | mitogen-activated protein kinase kinase |
| MKK1/7 | mitogen-activated protein kinase kinase 1 and 7 |
| MMP | matrix metalloproteinase |
| MT | malonyltransferase |
| MCP1 | monocyte chemoattractant protein 1 |
| MDA | malonaldehyde |
| MGO | methylglyoxal |
| NAD+ | nicotinamide adenine dinucleotide (oxidized form) |
| NADPH | nicotinamide adenine dinucleotide phosphate (reduced form) |
| NFATc1 | nuclear factor of activated T-cells cytoplasmic 1 |
| NFIL3 | nuclear factor interleukin-3-regulated protein |
| NF-κB | nuclear factor-kappa B |
| NGF | nerve growth factor |
| NIK | NF-κB-inducing kinase |
| nNOS | neuronal isoform of nitric oxide synthase |
| NO | nitrix oxide |
| NOX | NADPH oxidase |
| NOX4 | NAPDH oxidase 4 |
| NQO1 | NAD(P)H quinone oxidoreductase 1 |
| Nrf2 | nuclear factor erythroid 2 |
| OCN | osteocalcin |
| OPG | osteoprotegerin |
| PAL | phenylalanine ammonia lyase |
| p-AMPK | phosphorylated adenosine 5′-monophosphate-activated protein kinase |
| PARP | poly(ADP-ribose)-polymerase |
| PDK1/2 | 3-phosphoinositide–dependent protein kinase 1 and 2 |
| PEPCK | phosphoenolpyruvate carboxykinase |
| p-ERK | phosphorylated extracellular signal-regulated kinase |
| PG | prostaglandin |
| PGC-1α | peroxisome proliferator-activated receptor-gamma coactivator-1alpha |
| PGE2 | prostaglandin E2 |
| PGF2 | prostaglandin F2 |
| PI3K | phosphatidylinositol 3-kinase |
| PIP2 | phosphatidylinositol-4,5-biphosphate |
| PIP3 | phosphatidylinositol-3,4,5-triphosphate |
| PKA | protein kinase A (cAMP-dependent protein kinase) |
| PKC | protein kinase C |
| PLA2 | phospholipase A2 |
| PPARα | peroxisome proliferator-activated receptor-alpha |
| PPARγ | peroxisome proliferator-activated receptors-gamma |
| PTS | pterocarpan synthase |
| PYK | pyruvate kinase |
| RANKL | receptor activator of NF-κB ligand |
| RIP | receptor-interacting protein |
| ROS | reactive oxygen species |
| RUNX2 | runt-related transcription factor 2 |
| S1P and S2P | site-specific protease 1 and 2 |
| sAPP | soluble APP |
| SCAP | SREB cleavage-activating protein |
| SIRT1 | sirtuin 1 |
| SCD1 | stearoyl-CoA desaturase 1 |
| SGK1 | serine/threonine-protein kinase |
| SMI | structure model index |
| SOD | superoxide dismutase |
| SREB | sterol regulatory element binding |
| STAT1 | signal transducer and activator of transcription 1 |
| STEBp1 | SET-binding protein 1 |
| T3 | triiodothyronine |
| T4 | thyroxine |
| TAK1 | transforming growth factor β-activated kinase |
| TAT1 | signal transducer and activator of transcription 1 |
| TBARs | thiobarbituric acid reactive substances |
| Tb.N | trabecular number |
| Tb.Pf | trabecular pattern factor |
| Tb.Sp | trabecular separation |
| Tb.Th | trabecular thickness |
| TCF | T cell factor |
| TG | Triacylglycerol |
| TGF-α | transforming growth factor-alpha |
| TNF | tumor necrosis factor |
| TNF-α | tumor necrosis factor-alpha |
| TNFR | tumor necrosis factor receptor |
| TNFR1 | TNF receptor-1 |
| TORC2 | target of rapamycin complex 2 |
| TRADD | TNF receptor-associated death domain |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIL | TNF-related apoptosis-inducing ligand |
| TRAP | tartrate-resistant acid phosphatase |
| Ub | ubiquitination |
| UCP1 | uncoupling protein 1 |
| VR | vestitone reductase |
| Wnt/β-catenin | canonical Wnt pathway |
| XRE | xenobiotic response element |