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. 2021 Jul 16;10(7):1134. doi: 10.3390/antiox10071134

Figure 5.

Figure 5

OxiCAT and mass spectrometry analysis of oxidized cysteine residues in cTnI from myocardial biopsies of human HF patients. (A) Schematic representation of cTnI illustrates the different domains. (B) Amino acid sequence of cTnI with PKA, PKD, and PKC phosphorylation sites and the location of the oxidized cysteine residue. (C) Oxidized and cysteine residue of cTnI with the representative mass spectrometric sequence UniProtKB—P19429 (TNNI3_HUMAN), cardiac muscle, updated: 2 December 2020. The numbers indicate the percentage of oxidation. n = 2 per group.