Figure 8.

Proinflammatory cytokines and myocardial stress in HF cardiomyocytes. Concentration levels before and after reduced glutathione (GSH) treatment of (A) hydrogen peroxide (H₂O₂); (B) lipid peroxidation; (C) 3-nitrotyrosine; (D) nitric oxide (NO); (E) interleukin 6 (IL-6); (F) intercellular cell adhesion molecule-1 (ICAM-1); (G) vascular cell adhesion molecule-1 (VCAM-1); (H) tumor necrosis factor alpha (TNFα). Data are shown as mean ± SEM. * p < 0.05/** p < 0.001/**** p < 0.0001 donor baseline vs. HF baseline, † p < 0.05/†† p < 0.01/††† p < 0.001 before vs. after GSH. n = 8–10, hearts per group.