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. 2021 Jul 15;10(7):1129. doi: 10.3390/antiox10071129

Table 4.

Opinion of the scientific committee on consumer safety (SCCS) on the safety of the use of arbutin, α-arbutin, and deoxyarbutin in cosmetic products.

Literature Compounds Statements
Name Chemical Structure
[103] Arbutin 2 “The SCCS considers the use of β-arbutin to be safe for consumers in cosmetic products in a concentration up to 7% in face creams provided that the contamination of
hydroquinone in the cosmetic formulations remain below 1 ppm.”
[104] α-arbutin 3 “The SCCS considers the use of α-arbutin safe for consumers in cosmetic products in
a concentration up to 2% in face creams and up to 0.5% in body lotions.”
[105] Deoxyarbutin 22 “Therefore, the overall conclusion of the SCCS is that the use of deoxyarbutin
up to 3% in face creams is not safe.”