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. 2021 Jul 8;10(7):632. doi: 10.3390/biology10070632

Figure 2.

Figure 2

Genetic perturbations in S. cerevisiae for enhanced production of FAs. These genetic perturbations result in higher levels of FAs in S. cerevisiae. Once there is an excess of citrate in the cytosol, the gene responsible for converting citrate to acetyl-CoA, ACL (shown in red in the cytosol), is inserted into S. cerevisiae. These genetic perturbations result in higher levels of FAs in yeast. The strengthened steps involved in enhanced FA production are indicated in blue, and the blocked steps are indicated in red color.