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. 2021 Jul 9;8:684528. doi: 10.3389/fcvm.2021.684528

Table 1.

Comparison between patients with CAC score 0 and those with CAC score ≥1.

Total (n = 280) CAC score = 0 (n = 131) CAC score ≥ 1 (n = 149) p-value
Age (years) 63.2 ± 16.7 53.7 ± 13.1 72.7 ± 13.2 <0.001
Weight (kg) 80.5 ± 16.7 84.4 ± 16.3 76.6 ± 15.8 <0.001
BMI (kg/m2) 27.8 ± 5.2 28.9 ± 5.2 26.8 ± 4.9 0.001
Male gender (n, %) 161 (57.5) 76 (58.0) 76 (60.3) 0.707
History
Heart failure (n, %) 6 (2.1) 1 (0.8) 5 (4.0) 0.089
Valve disease (n, %) 6 (2.1) 1 (0.8) 5 (4.0) 0.089
Atrial fibrillation (n, %) 14 (5.0) 3 (2.2) 11 (7.3) 0.023
CKD (n, %) 32 (11.4) 9 (6.9) 23 (18.3) 0.006
Chronic pulmonary disease (n, %) 43 (15.3) 20 (15.2) 23 (15.4) 0.718
Cancer (n, %) 28 (10) 7 (5.3) 21 (16.7) 0.004
Risk factors
Hypertension (n, %) 128 (45.7) 40 (30.5) 78 (61.9) <0.001
DM (n, %) 64 (22.8) 33 (25.2) 31 (24.6) 0.913
Dyslipidemia (n, %) 89 (31.8) 39 (29.8) 50 (39.7) 0.095
Smoking (n, %) 30 (10.7) 13 (9.9) 17 (13.5) 0.373
Laboratory values
Hemoglobin (g/dl) 13.5 ± 1.8 13.7 ± 1.7 13.4 ± 2.0 0.205
Platelets (103/mm3) 218.4 ± 86.8 218.3 ± 84.1 212.2 ± 86.5 0.572
WBC (103/mm3) 7.8 ± 4.4 7.2 ± 3.0 8.1 ± 5.0 0.072
CRP (mg/L) 135.7 ± 96.5 128.0 ± 97.9 140.1. 94.1 0.312
D-dimers (ng/ml) 1,638.6 ± 2,720.7 1,048.5 ± 1,442.4 1,830.9 ± 2,613.0 0.042
LDH (U/L) 968.4 ± 1,183.8 988.6 ± 608.8 1,000.3 ± 595.8 0.877
Lactate (mmol/L) 1.0 ± 0.6 1.0 ± 0.5 1.1 ± 0.6 0.659
cTnT (μg/L) 0.02 ± 0.04 0.01 ± 0.01 0.02 ± 0.01 <0.001
Creatinine (mg/dl) 1.2 ± 1.2 1.0 ± 0.9 1.3 ± 1.4 0.012
Chest CT
Ground-glass opacity (n, %) 226 (80.7) 115 (87.7) 111 (74.4) 0.854
Interlobular septal thickening (n, %) 25 (8.9) 9 (6.8) 17 (11.4) 0.076
Pulmonary consolidation (n, %) 94 (33.5) 44 (33.5) 50 (33.5) 0.267
Pleural effusion (n, %) 14 (5.0) 4 (3.0) 10 (6.7) 0.068
ICU admission (n, %) 71 (18.2) 33 (25.1) 39 (26.1) 0.500

BMI, body mass index; CKD, chronic kidney disease; DM, diabetes mellitus; WBC, white blood cells; NLR, neutrophil to lymphocyte ratio; CRP, C-reactive protein; LDH, lactate dehydrogenase; cTnT, cardiac troponin T; CT, computed tomography; ICU, intensive care unit; CAC, coronary artery calcium.