Table 1.
Demographic, clinical and follow-up data of 40 patients with various neuropathic pain syndromes.
| Pre-Operatively | FU I | FU II | FU III | FU IV | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nr | Sex | Age | Diagnosis | Etiology/Category of Pain | D/Pain | Body Part Affected |
VAS Max |
VAS Ave |
IPG | Stim Site |
VAS Max |
VAS Ave |
Stim Site |
VAS Max |
VAS Ave |
Stim Site |
VAS Max |
VAS Ave |
Stim Site |
VAS Max | VAS Ave |
| 1 | M | 45 | Poststroke/central | Brainstem infarction | 2y | Face/Head | 10 | 7 | yes | CM-Pf | 0 | 0 | CM-Pf | 0 | 0 | CM-Pf | 7 | 3 | CM-Pf | 7 | 3 |
| 2 | M | 72 | Postherpetic | Herpes zoster | 2y | Head C2 L | 8 | 4 | yes | CM-Pf | 0 | 0 | CM-Pf | 0 | 0 | CM-Pf | 1 | 0 | - | - | - |
| 3 | M | 87 | Postherpetic | Herpes zoster | 2y | Thorax T3-6 R |
10 | 6 | yes | CM-Pf | 3 | 0 | - | - | - | - | - | - | - | - | - |
| 4 | F | 50 | Poststroke/ central |
Multiple sclerosis | 2y | Arm L | 10 | 5 | yes | CM-Pf | 6 | 3 | CM-Pf | 6 | 3 | CM-Pf | 6 | 3 | CM-Pf | 8 | 3 |
| 5 | F | 67 | Central thalamic | Thalamic hemorrhage | 2y | Hemibody | 10 | 9 | no | - | - | - | - | - | - | - | - | - | - | ||
| 6 | M | 52 | Central thalamic | Thalamic hemorrhage | 1y | Hemibody | 8 | 6 | yes | CM-Pf | 5 | 4 | - | - | - | - | - | - | - | ||
| 7 | F | 48 | Facial pain | Trigeminal nerve surgery | 23y | Face R | 10 | 7 | yes | CM-Pf | 2 | 1 | CM-Pf | 3 | 2 | CM-Pf | 4 | 3 | CM-Pf | 6 | 4 |
| 8 | F | 40 | CRPS | Knee surgery | 10y | Leg L | 10 | 8 | yes | CM-Pf | 7 | 4 | CM-Pf | 5 | 4 | CM-Pf | 5 | 3 | CM-Pf | 4 | 3 |
| 9 | M | 73 | Postherpetic | Herpes zoster | 2y | Face R | 7 | 6 | yes | CM-Pf | 0 | 0 | CM-Pf | 0 | 0 | CM-Pf | 0 | 0 | CM-Pf | 0 | 0 |
| 10 | M | 72 | Phantom limb pain | Amputation | 35y | Leg L | 8 | 5 | yes | CM-Pf | 10 | 8 | CM-Pf | 6 | 5 | CM-Pf | 5 | 4 | - | - | - |
| 11 | F | 42 | Brachial plexus injury | Motorbike accident | 6y | Arm R | 9 | 9 | yes | CM-Pf | 2 | 2 | CM-Pf | 3 | 2 | CM-Pf | 2 | 1 | CM-Pf | 2 | 1 |
| 12 | F | 56 | Facial pain | Dental surgery | 14y | Face R | 10 | 5 | yes | CM-Pf | 7 | 4 | CM-Pf | 0 | 0 | CM-Pf | 2 | 1 | CM-Pf | 0 | 1 |
| 13 | F | 50 | Poststroke/central | Sclerodermia | 18y | Arm R | 7 | 4 | yes | CM-Pf | 3 | 1 | CM-Pf | 4 | 2 | CM-Pf | 3 | 2 | - | - | - |
| 14 | M | 54 | Central thalamic | Mesencephalic hemorrhage | 3y | Face/Arm R | 8 | 6 | no | - | - | - | - | - | - | - | - | - | - | ||
| 15 | M | 65 | Poststroke/central | Basal ganglia hemorrhage | 2y | Arm L | 9 | 9 | yes | CM-Pf | 8 | 6 | CM-Pf | 8 | 6 | CM-Pf | 7 | 5 | CM-Pf | 7 | 5 |
| 16 | M | 70 | Central thalamic | Thalamic infarction | 10y | Hemibody | 8 | 7 | no | - | - | - | - | - | - | - | - | - | - | ||
| 17 | M | 63 | Poststroke/central | Pontomesencephalic infarction | 10y | Leg R | 10 | 9 | yes | VPL | 5 | 4 | VPL | 6 | 5 | VPL | 7 | 5 | - | - | - |
| 18 | M | 34 | CRPS | Riding accident | 5y | Hand R | 10 | 9 | no | - | - | - | - | - | - | - | - | - | |||
| 19 | M | 33 | Brachial plexus injury | Motorbike accident | 14y | Arm L | 9 | 7 | yes | VPL | 3 | 2 | VPL | 3 | 2 | VPL | 7 | 4 | VPL | 2 | 2 |
| 20 | M | 52 | Spinal cord lesion | Car accident | 4y | Hand R | 8 | 7 | no | - | - | - | - | - | - | - | - | - | - | - | |
| 21 | M | 65 | Poststroke/ central |
Frontoparietal infarction | 3y | Hemibody | 7 | 6 | yes | CM-Pf | 4 | 2 | CM-Pf | 4 | 2 | - | - | - | - | - | |
| 22 | F | 72 | Facial pain | Trigeminal nerve surgery | 18y | Face R | 10 | 9 | yes | VPM | 4 | 2 | VPM | 5 | 2 | VPM | 5 | 3 | VPM | 0 | 0 |
| 23 | M | 40 | Spinal cord lesion | Accident | 4y | Arm R | 10 | 8 | yes | CM-Pf | 3 | 2 | CM-Pf | 2 | 1 | CM-Pf | 2 | 1 | CM-Pf | 10 | 7 |
| 24 | F | 58 | CRPS | Ulnar nerve surgery | 2y | Arm R | 10 | 8 | yes | VPL | 4 | 2 | VPL | 4 | 2 | VPL | 4 | 2 | VPL | 5 | 4 |
| 25 | M | 47 | Facial pain | Maxillary sinus surgery | 8y | Face L | 10 | 9 | yes | VPL | 5 | 4 | VPL | 5 | 4 | VPL | 8 | 7 | VPL | 7 | 6 |
| 26 | F | 24 | CRPS | Injury of fingers | 4y | Hand R | 10 | 9 | yes | CM-Pf | 10 | 9 | VPL | 10 | 9 | CM-Pf | 10 | 9 | - | - | - |
| 27 | F | 57 | CRPS | Shoulder luxation | 2y | Arm R | 10 | 8 | yes | VPL | 3 | 2 | VPL | 3 | 2 | - | - | - | - | - | |
| 28 | F | 50 | Peripheral nerve injury |
Inguinal nerve surgery | 3y | Thigh L | 9 | 6 | yes | VPL | 7 | 5 | VPL | 5 | 4 | VPL | 8 | 6 | Both | 7 | 4 |
| 29 | F | 31 | CRPS | Hand surgery | 6y | Hand R | 9 | 8 | yes | CM-Pf | 9 | 8 | CM-Pf | 9 | 8 | - | - | - | - | - | |
| 30 | F | 44 | CRPS | Ulnar nerve surgery | 10y | Arm L | 9 | 8 | yes | VPL | 2 | 2 | VPL | 10 | 9 | CM-Pf | 10 | 7 | - | - | - |
| 31 | F | 43 | Facial pain | Dental surgery | 2y | Face L | 10 | 6 | yes | VPM | 6 | 5 | VPL | 9 | 6 | VPL | 9 | 6 | VPM | 9 | 6 |
| 32 | F | 68 | Facial pain | Trigeminal nerve surgery | 3y | Face L | 8 | 8 | no | - | - | - | - | - | - | - | - | - | |||
| 33 | F | 26 | CRPS | Accident | 55y | Arm L | 9 | 8 | yes | VPL | 6 | 5 | VPL | 9 | 8 | VPL | 9 | 8 | VPL | 7 | 5 |
| 34 | M | 53 | Brachial plexus injury | Motorbike accident | 4y | Arm R | 9 | 6 | yes | CM-Pf | 10 | 5 | CM-Pf | 10 | 5 | CM-Pf | 4 | 3 | CM-Pf | 4 | 3 |
| 35 | M | 55 | Poststroke/ central |
Basilary artery thrombosis | 5y | Hemibody | 7 | 4 | yes | VPL | 5 | 4 | VPL | 5 | 4 | VPL | 4 | 5 | VPL | 7 | 2 |
| 36 | M | 49 | FBSS | Spinal surgery | 5y | Leg L | 9 | 8 | yes | VPL | 8 | 6 | VPL | 8 | 5 | VPL | 4 | 2 | - | - | - |
| 37 | F | 70 | Spinal cord lesion | Dural AV fistula embolisation | 3y | Arm L | 9 | 9 | yes | VPL | 10 | 8 | VPL | 7 | 7 | - | - | - | - | - | - |
| 38 | F | 69 | Spinal cord lesion | Car accident | 10y | Legs L/R | 7 | 4 | yes | CM-Pf | 10 | 8 | - | - | - | - | - | - | - | - | - |
| 39 | M | 56 | Postherpetic | Herpes zoster | 3y | ThoraxT 10-11 | 10 | 9 | no | - | - | - | - | - | - | - | - | - | - | - | |
| 40 | F | 57 | FBSS | Spinal surgery | 9y | Leg L | 10 | 8 | yes | CM-Pf | 10 | 9 | CM-Pf | 8 | 7 | - | - | - | - | - | - |
CM–Pf = centromedian–parafascicular nucleus, VPL = ventroposterolateral nucleus (thalami); VPM = ventroposteromedial nucleus (thalami), D/pain = duration of pain, stim site = stimulation site, FBSS = failed back surgery syndrome, CRPS = complex regional pain syndrome. Note that patients with thalamic lesions are not included in the “poststroke/central” group, but listed separately as “central/thalamic”.