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. 2021 Jun 23;9(7):715. doi: 10.3390/biomedicines9070715

Figure 5.

Figure 5

Mental Health: Neuropsychiatric-like phenotype and cognitive impairment in Dark and light box test (A) and T-Maze test (B). Results are expressed as the mean ± SEM. Male NTg, n = 8 (White circles for individual values; white bar, mean value); male 3xTg-AD n = 9 (Yellow circles, individual values of heterozygous 3xTg-AD +/− mice, n = 5; blue circles, individual values for homozygous 3xTg-AD +/+ mice, n = 4; yellow and blue bars, mean value for heterozygous and homozygous 3xTg-AD genotypes, respectively, since genotype-load differences were found). Statistics: one-way analysis of variance (ANOVA) for comparisons between all the groups of mice followed by Bonferroni’s post hoc test. * p < 0.05, ** p < 0.01, vs. homozygous 3xTg-AD-group.