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. 2021 Jul 13;10(7):661. doi: 10.3390/biology10070661

Figure 2.

Figure 2

Imiquimod inhibits HIV p24 expression. (A) Macrophages were treated with or without imiquimod at indicated concentrations for 24 h prior to infection with different HIV strains (Bal, YU2, and Jago). Cellular and culture supernatant proteins were collected on day 9 post-infection and subjected to the Western blot assay for HIV p24 expression. (B) The morphology of uninfected macrophages comparing with HIV Bal-infected cells pretreated with or without imiquimod (10 μg/mL) was photographed by a confocal microscope (Nikon, A1R, Tokyo, Japan) on day 9 post-infection. The arrows indicate HIV-induced giant syncytium formation in macrophages.