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Schematic representation of beta-cell intracellular mechanisms involved in insulin secretion. Adenosine diphosphate (ADP), adenosine triphosphate (ATP), calcium (Ca2+), glucagon-like peptide-1 (GLP-1), glucose transporter 1 (GLUT1), G-protein coupled receptor 6A (GPRC6A), inositol-1,4,5-trisphosphate (IP3), plasma membrane (PM), osteocalcin (OCN), oxidative phosphorylation (OxPhos), phospholipase C (PLC), potassium (K+).
