Figure 9.

Neuropathologic scoring (necrosis + karyopiknosis) (0–8) (a–h), and microglial recruitment scoring (0–3) (i–l) in cerebral and cerebellar cortex, hypothalamus/thalamus and hippocampus after therapy (saline 5 mL/kg (white bars), BPC 157 10 µg/kg (light gray bars), 10 ng/kg (dark gray bars) given intragastrically at 1 min ligation time). Neuropathologic scoring (necrosis + karyopiknosis) (0–8) (a–h). Assessment carried out at 15 min, 24 h, and 48 h ligation-time (a–d) and at 1 min, 5 min and 10 min therapy-time (e–h). Microglial recruitment scoring (0–3) (i–l). Assessment at 15 min, 24 h, and 48 h ligation-time. Microglial recruitment was not present at 1 min, 5 min and 10 min therapy-time (data not specifically shown). The effects of the intraperitoneal and local application regimen, providing the similar results were not specifically shown. MIN/MED/MAX, * p ˂ 0.05, at least vs. corresponding control.