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. 2021 Jul 14;9(7):815. doi: 10.3390/biomedicines9070815

Figure 1.

Figure 1

The effects of ischemia-reperfusion (IR) injury and delayed contralateral nephrectomy (Nx) on miRNA expression in the kidneys 8 days after IR and 1 day after Nx based on the miRNA microarray. The level of significance (given as −log10 p value) is plotted against the fold change (FC, given as log2FC). Vertical lines mark 1.5× and 2× FC, while the horizontal line marks the significance level (p < 0.05). (A): Effect of IR (IR-S vs. S-S). ▪: miRNAs selected for validation by qPCR; 1: mmu-miR-21a-5p, 2: mmu-miR-2137, 3: mmu-miR-142-3p, 4: mmu-miR-762, 5: mmu-miR-223-3p, 6: mmu-miR-142-5p, 7: mmu-miR-2861, 8: mmu-miR-3102-5p, 9: mmu-miR-199a-5p, 10: mmu-miR-199a-3p/mmu-miR-199b-3p, 11: mmu-miR-214-3p, 12: mmu-miR-146a-5p, 13: mmu-miR-21a-3p, 14: mmu-miR-129-1-3p. (B): Effects of Nx (IR-Nx vs. IR-S).