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The covariance matrix constructed from the whole MD trajectory fraction of motion of the first 10 eigenvectors plotted against the corresponding eigenvector. The first 10 eigenmodes were used to calculate the percentage fraction of motion of each eigenvector for RdRp-apo (A) and RdRp-RDV (C), and the fraction of motions by a single eigenvector for RdRp-apo (B) and RdRp-RDV complex (D).
