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. 2021 Jul 13;10(7):658. doi: 10.3390/biology10070658

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Stage/IOP-dependent alterations in the content of signaling lipids in AH of POAG patients. The results of partial least square discriminant analysis (PLS-DA) revealing AH compounds distinguishing glaucoma patients with Stage IIA (A), Stage IIB (B), Stage IIIB (C) or Stage IIIC (D) POAG from the control individuals (CONT). The PLS-DA data regarding comparison of AH contents of signaling lipids in patients with different POAG stages regardless IOP levels are also presented (E). The explained variance of each component is indicated on the axes. Variable importance in projection (VIP) scores exceeding a cutoff value of 1.5 are considered.