Figure 2.

Incisor analyses of the rat and rabbit based on cone beam computed tomography (CBCT) and µCT. (A) Lateral view of a rat hemi-mandible: On the lingual (inner) surface of the incisor the short line (red) is a tracing of the path between the bony alveolus and occlusal (gnaw) ridge. The curved (green) tracing above marks out the path length of the occlusal surface (from gnaw ridge to tip) of the incisor. On the labial (outer) surface, the orange line traces the path length from the bony alveolus to the tip. Note the path of the incisor reserve crown (root) as it curves under the cheek teeth (arrow); more posteriorly it is not sufficiently mineralized to be radiopaque. In the ramus the defect designs are marked out; ‘a’ indicates the CSD, ‘b’ indicates the ID, and ‘c’ indicates the CRO. (B) Rabbit incisor: The path length of the labial surface was measured in the rabbit (orange tracing) as was the occlusal surface angle relative to the horizontal—mandibles from subsequent time points were registered to baseline scans as noted in the methods. (C) Defect design in the rabbit. The tracings indicate the CSD (a), body defect (b), ID (c), and CRO (d). Note that the CRO tracing for both the rat and rabbit more closely approximates the wide gap osteotomy but is not to scale. CBCT = cone beam computed tomography, µCT = micro computed tomography, CSD = critical size defect. ID = intermediate defect, CRO = complete ramus osteotomy.