Table 3. List of patients, karyotypes, and fusion genes detected in the RNA target sequencing data of the smear samples.
| Patient | Clinical diagnosis | Karyotype | Mapped reads | Detected fusion gene | RPM |
|---|---|---|---|---|---|
| #097 | AML | 46,XY,t(8;21)(q22;q22)[17]/46,XY[3] | 33369 | RUNX1-RUNX1T1 | 13828 |
| #112 | AML | 46,XX,inv(16)(p13.1q22)[20] | 35387 | CBFB-MYH11 | 2560 |
| #152 | AML-MRC | 46,XX[20] | 48535 | KMT2A-MLLT10 | 1551 |
| #176 | AML | 46,XY[20] | 44467 | - | - |
| #188 | aCML | 47,XY,+6[20] | 20447 | - | - |
| #191 | AML | 46,XX[20] | 84383 | - | - |
| #205 | AML | 46,XY[20] | 27515 | - | - |
| #220 | t-AML | 46,XX,inv(16)(p13.1q22)[20] | 48261 | CBFB-MYH11 | 2546 |
| #226 | AML | 46,XX,i(7)(p10),-9,-9,+mar1,+mar2[20] | 31830 | - | - |
| #231 | MPAL | 46,XY,add(17)(p11.2)[12]/46,XY,del(17)(p?)[6]/46,XY[2] | 167249 | NUP214-ABL | 2255 |
| #232 | AML | 46,XY,del(11)(p?)[1]/46,XY[19] | 50825 | - | - |
| #238 | AML-MRC | 46,XY,t(4;12)(q12;p13)[14]/46,XY[6] | 30749 | ETV6-CHIC2 | 1524 |
| #240 | AML | 46,XY,t(8;21)(q22;q22.1)[3]/46,idem,-Y[14]/46,idem,del(9)(q?)[2]/46,XY[1] | 56151 | RUNX1-RUNX1T1 | 166556 |
| #248 | AML | 46,XX,+8[2]/46,XX[18] | 13875 | - | - |
| #256 | AML | 47,XY,+10[3]/46,XY[17] | 35635 | - | - |
AML, acute myeloid leukemia; t, therapy-related; AML-MRC, AML with myelodysplasia-related changes; aCML, atypical chronic myeloid leukemia; MPAL, mixed phenotype acute leukemia, t-AML, therapy-related acute myeloid leukemia.