Table 4. Descriptive summary of the effects of tocotrienols supplementation on oxidative stress markers, antioxidant enzyme activities and antioxidant response.
Biomarkers | Summary of findings and reference |
---|---|
PC | ↓ [18], ↔ [17] |
AGEs | ↔ [18,33] |
TBARS | ↓ [25], ↔ [19] |
LOPs | ↔ [25] |
LDL oxidation rate | ↓ [29] |
SOD | ↓ [18], ↑ [16] |
CAT | ↔ [16,18] |
GPx | ↔ [16,18] |
GSH | ↔ [16] |
Antioxidant response | ↑ TAS (320 mg/day) [31], ↔ TAP or TAC [19,23] |
Symbol: ↓, significant reduction, ↑, significant increase, ↔, no effect.
Abbreviations: AGEs, advanced glycation end-products, CAT, catalase, GPx, glutathione peroxidase, GSH, glutathione, LDL, low density lipoprotein, LOPs, lipid peroxidation products, PC, protein carbonyl, SOD, superoxide dismutase, TAC, total antioxidant capacity, TAP, total antioxidant power, TAS, total antioxidant status, TBARS, thiobarbituric acid reactive substances.