Table 4. GDM diagnosed at inclusion (in first trimester) compared to GDM diagnosed later in pregnancy.
a) GDM after WHO 1999 criteria, N = 195: | ||||
GDM | p-value | |||
Early GDM | Late GDM | |||
N (%) | 77 (39) | 118 (61) | ||
Baseline data | Age, years | 31.5 ± 4.2 | 29.6 ± 4.6 | 0.004 |
Nulliparity | 36 (46) | 66 (55) | 0.10 | |
BMI, kg/m2 | 30.5 ± 6.2 | 29.0 ± 6.7 | 0.11 | |
Weight, kg | 83.8 ± 16.8 | 80.5 ± 18.8 | 0.21 | |
Comorbidity | 32 (42) | 62 (53) | 0.13 | |
Smoking | 4 (5) | 6 (5) | 0.97 | |
Maternal outcome | HT | 1 (1) | 5 (4) | 0.22 |
PE | 4 (5) | 5 (4) | 0.76 | |
Preterm birth | 3 (4) | 6 (5) | 0.65 | |
Weight gain, kg * | 7.0 ± 4.8 | 9.0 ± 5.7 | 0.015 | |
Gest. age, days | 269 ± 34 | 276 ± 12 | 0.032 | |
Insulin treatment | 17 (22) | 6 (5) | <0.001 | |
Neonatal outcome | Birth weight, g | 3337 ± 793 | 3507 ± 552 | 0.08 |
Birth weight, z-score | -0.19 ± 1.09 | -0.10 ± 1.10 | 0.58 | |
SGA/LGA § | 9 (12)/6 (8) | 16 (14)/13 (12) | 0.78 | |
b) GDM after WHO 2013 criteria, N = 284: | ||||
GDM | p-value | |||
GDM at incl | Late GDM | |||
N (%) | 160 (56) | 124 (44) | ||
Baseline data | Age, years | 30.8 ± 4.6 | 29.4 ± 4.4 | 0.008 |
Nulliparity | 90 (56) | 72 (58) | 0.61 | |
BMI, kg/m2 | 31.1 ± 6.4 | 29.9 ± 6.8 | 0.13 | |
Weight, kg | 86.6 ± 18.4 | 83.4 ± 20.0 | 0.16 | |
Comorbidity | 83 (52) | 66 (53) | 0.82 | |
Smoking | 6 (4) | 9 (7) | 0.19 | |
Maternal outcome | HT | 7 (4) | 7 (6) | 0.73 |
PE | 9 (6) | 10 (8) | 0.41 | |
Preterm birth | 7 (4) | 9 (7%) | 0.30 | |
Weight gain, kg * | 8.3 ± 5.4 | 9.9 ± 5.7 | 0.031 | |
Gest. age, days | 271 ± 30 | 276 ± 17 | 0.10 | |
Insulin treatment | 20 (13) | 4 (3) | 0.005 | |
Neonatal outcome | Birth weight, g | 3505 ± 718 | 3518 ± 641 | 0.88 |
Birth weight, z-score | 0.03 ± 1.07 | -0.02 ± 1.09 | 0.69 | |
SGA/LGA § | 15 (10)/15 (10) | 14 (11)/14 (11) | 0.80 |
a) Values given as mean ± SD or N (%) as appropriate. HT hypertension, PE preeclampsia, SGA small for gestational age, LGA large for gestational age. * N = 175, § N = 191.
b) Values given as mean ± SD or N (%) as appropriate. HT hypertension, PE preeclampsia, SGA small for gestational age, LGA large for gestational age. * N = 247, § N = 277.