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. 2021 Jul 23;16(7):e0254895. doi: 10.1371/journal.pone.0254895

Table 4. GDM diagnosed at inclusion (in first trimester) compared to GDM diagnosed later in pregnancy.

a) GDM after WHO 1999 criteria, N = 195. b) GDM after WHO 2013 criteria, N = 284.

a) GDM after WHO 1999 criteria, N = 195:
GDM p-value
Early GDM Late GDM
N (%) 77 (39) 118 (61)
Baseline data Age, years 31.5 ± 4.2 29.6 ± 4.6 0.004
Nulliparity 36 (46) 66 (55) 0.10
BMI, kg/m2 30.5 ± 6.2 29.0 ± 6.7 0.11
Weight, kg 83.8 ± 16.8 80.5 ± 18.8 0.21
Comorbidity 32 (42) 62 (53) 0.13
Smoking 4 (5) 6 (5) 0.97
Maternal outcome HT 1 (1) 5 (4) 0.22
PE 4 (5) 5 (4) 0.76
Preterm birth 3 (4) 6 (5) 0.65
Weight gain, kg * 7.0 ± 4.8 9.0 ± 5.7 0.015
Gest. age, days 269 ± 34 276 ± 12 0.032
Insulin treatment 17 (22) 6 (5) <0.001
Neonatal outcome Birth weight, g 3337 ± 793 3507 ± 552 0.08
Birth weight, z-score -0.19 ± 1.09 -0.10 ± 1.10 0.58
SGA/LGA § 9 (12)/6 (8) 16 (14)/13 (12) 0.78
b) GDM after WHO 2013 criteria, N = 284:
GDM p-value
GDM at incl Late GDM
N (%) 160 (56) 124 (44)
Baseline data Age, years 30.8 ± 4.6 29.4 ± 4.4 0.008
Nulliparity 90 (56) 72 (58) 0.61
BMI, kg/m2 31.1 ± 6.4 29.9 ± 6.8 0.13
Weight, kg 86.6 ± 18.4 83.4 ± 20.0 0.16
Comorbidity 83 (52) 66 (53) 0.82
Smoking 6 (4) 9 (7) 0.19
Maternal outcome HT 7 (4) 7 (6) 0.73
PE 9 (6) 10 (8) 0.41
Preterm birth 7 (4) 9 (7%) 0.30
Weight gain, kg * 8.3 ± 5.4 9.9 ± 5.7 0.031
Gest. age, days 271 ± 30 276 ± 17 0.10
Insulin treatment 20 (13) 4 (3) 0.005
Neonatal outcome Birth weight, g 3505 ± 718 3518 ± 641 0.88
Birth weight, z-score 0.03 ± 1.07 -0.02 ± 1.09 0.69
SGA/LGA § 15 (10)/15 (10) 14 (11)/14 (11) 0.80

a) Values given as mean ± SD or N (%) as appropriate. HT hypertension, PE preeclampsia, SGA small for gestational age, LGA large for gestational age. * N = 175, § N = 191.

b) Values given as mean ± SD or N (%) as appropriate. HT hypertension, PE preeclampsia, SGA small for gestational age, LGA large for gestational age. * N = 247, § N = 277.