Clinical research |
With nanopore technology, the long read can help researchers to identify and phase genetic variant, and fully characterize novel isoforms and fusion transcripts. Nanopore technology gives a new insight to health and disease, from cancer, immunology, to neuroscience. The representing references are [61,62,63,64,65,66] |
Detection of microbes |
The nanopore technology can be used to sequence the DNA or RNA sequence of microbes, and it helps researchers to classify or monitor the microbes. Moreover, it is promising to establish microbe surveillance and response quickly during pandemic, if the nanopore technology can be applied in the area of public health. The representing references are [34,35,67,68] |
Assemble genomes |
Owing to the long-read sequencing ability, nanopore sequencing technology can overcome the problems that short-read sequence devices meet in area the long-repeated fragments. The representing references are [35,69,70,71] |
Environmental genomics |
The portable and affordable nanopore sequencing technology provides a unique tool for environmental research, including biodiversity assessment, pathogen identification and animal conservation. Besides, the real-time data analysis provides immediate access to results, whether in labs or in the field. The representing references are [72,73,74] |