Table 2.
Material | Reasoning for Efficacy |
---|---|
Polytetrafluoroethylene (PTFE) | Physiologically inert Low adhesiveness with cells/tissues Separates damaged surfaces during wound healing without degradation Biocompatible |
Polylactic acid (PLA) | No specific binding site with cells/tissues on polymer matrix Low adhesiveness with cells/tissues Separates damaged surfaces during wound healing without degradation Biocompatible (FDA approval for human use in orthopedic and neurosurgical operations) Biodegradable |
Polyethylene glycol (PEG) | High mobility and steric stabilization effects in aqueous solution Low adhesiveness with cells/tissues Biocompatible |
PLA-PEG | Low adhesiveness with cells/tissues Flexible and hydrophilic Biocompatible Biodegradable |
Hyaluronic Acid (HA) | Wound healing properties High viscosity when dissolving by water or body fluid Muco-adhesive property in solid state Biocompatible Bioresorbable |
Alginate (ALG) | Wound healing properties Muco-adhesive property in solid state Partially crosslinking by multi-valence positive charged ions in body fluid Biocompatible Bioresorbable |
Cellulose (oxidized regenerated) (ORC) | Wound healing properties, in terms of re-epithelialization Muco-adhesive property in solid state Biocompatible Bioresorbable |
Carboxymethyl cellulose (CMC) | Remained on the injury surfaces during wound healing Muco-adhesive property in solid state Delayed bioresorption Biocompatible |
Icodextrin | Metabolized into oligosaccharides by the α-amylase in the body Delayed bioresorption in peritoneal cavity Remained on the injury surfaces during wound healing Biocompatible |