Table 1.

Putative treatment strategies that aim to reduce immunosuppression during sepsis.

Treatment	Target & Action	Reference
GM-CSF	Increase activity and production of innate immune cells i.e., neutrophils	[116]
G-CSF	Increase innate immunity	[117]
IFN-γ	Increase leukocyte activity	[104]
IL-3	Induction of myelopoiesis	[46]
IL-7	Promotes proliferation and survival of lymphocytes	[112]
IL-15	Maintenance of NK cell population	[118]
Broad spectrum IgG	Regulate pro- and anti-inflammatory processes	[119]
Anti-PD1/PD-L1	Reduce cell death and promote T-cell responses	[120]
Anti-CTLA-4	Reduce cell death and promote T-cell proliferation	[121]