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Schematic representation of human leptin sequence. Helix A (amino acid residues 3–26, IQKVQDDTKTLIKTIVTRINDISH); Helix B (amino acid residues 50–68, TLSKMDQTLAVYQQILTSM); Helix C (amino acid residues 71–93, RNVIQISNDLENLRDLLHVLAFS); Helix D (amino acid residues 120–142, STEVVALSRLQGSLQDMLWQLDL).
