Table 2.
Clinical Parameters | Genotype n (%) | p | ||
---|---|---|---|---|
CC | CT | TT | ||
pT | ||||
Tis | 10 (3.6%) | 0 (0.0) | 0 (0.0) | |
T1 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0.04 |
T2 | 12 (4.3%) | 10 (3.6%) | 0 (0.0%) | |
T3 | 115 (41.2%) | 50 (17.9%) | 11 (3.9%) | |
T4 | 50 (17.9%) | 15 (5.4%) | 6 (2.2%) | |
pN | ||||
N0 | 113 (40.5%) | 28 (10.0%) | 0 (0.0) | 0.19 |
N1 | 40 (14.3%) | 26 (9.3%) | 10 (3.6%) | |
N2 | 34 (12.2%) | 21 (7.5%) | 7 (2.5%) | |
M | ||||
M0 | 140 (50.1%) | 60 (21.5%) | 9 (3.2%) | 0.03 |
M1 | 47 (16.8%) | 15 (5.4%) | 8 (2.9%) | |
Tumor location | ||||
•sigmoid colon | 80 (29.7%) | 16 (5.7%) | 0 (0.0) | |
•cecum and ascending colon | 63 (22.6%) | 15 (5.4%) | 0 (0.0) | 0.04 |
•rectum | 28 (10.0%) | 15 (5.4%) | 9 (3.2%) | |
•transverse colon | 6 (2.2%) | 25 (9.0%) | 8 (2.9%) | |
•descending colon | 10 (3.6%) | 4 (1.4%) | 0 (0.0) |
Tis: carcinoma in situ, T1: tumor invades submucosa, T2: tumor invades muscularis propria, T3: tumor invades through the muscularis propria into pericolorectal tissues, T4: tumor penetrates to the surface of the visceral peritoneum, N0: no regional lymph node metastasis, N1: metastasis in 1–3 regional lymph nodes, N2: metastasis in 4 or more regional lymph nodes, M0: no distant metastasis, M1: metastasis to distant organs.