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(A) Antiangiogenic effect of 1a, 1b, 2 (10 µM) or vehicle DMSO in Zebrafish embryos after 48 h exposure. Images are representative of at least 20 identically treated fish. (B) The area of sub-intestinal veins (SIV) depicted as the mean ± SD of at least 20 embryos (n = 20 per group). *: p < 0.05; ****: p < 0.0001, One-way ANOVA with Dunnett’s multiple comparison test (GraphPad Prism 7).
