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The estimated stem-cell frequency (1/X) of the GSCs GS-5, NCH644 and the primary culture 17/02 after treatment with solvent (DMSO) or 1a or 1b with the IC25 and IC50 (n = 24 per group).
| Compound | DMSO | 1a | 1b | ||
|---|---|---|---|---|---|
| Stem-Cell Frequency (1/X) | IC25 | IC50 | IC25 | IC50 | |
| GS-5 | 196 | 305 | 357 | 839 | 1199 |
| NCH644 | 8 | 145 | 131 | 104 | 5626 |
| 17/02 | 216 | 1680 | 4288 | 5169 | 11,319 |
