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. 2021 Jul 20;11(7):1062. doi: 10.3390/biom11071062

Figure 2.

Figure 2

Pregnancies at term exhibit less impact on TGCs. Full-thickness H&E-stained placentas at E17.5 (A–D). Control dams exhibiting normal placental development at E17.5 (A,B). Placentas surviving to term in endometrial VEGF-overexpressing dams at E17.5 showing changes in TGCs (indicated by white arrows within the insets, C,D) but no discernible effect on maternal blood spaces in the placenta (C,D) compared to the controls (A,B). De, decidua; La, labyrinth; TGC, trophoblast giant cells. Scale bar in A and C = 500 µm. Scale bar in B and D = 50 µm.