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Differences in the regulation of the renin–angiotensin system in women vs. men. Abbreviations: ACE, angiotensin-converting enzyme; +, addition; AGT, angiotensinogen gene; AT1R, angiotensin II receptor type 1; AT2R, angiotensin II receptor type 2; DD, dominant homozygote of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene; ↓, decrease; ↑, increase; −, inhibition; REN, renin gene.
