Figure 1.

BmooMPα-I induces production of PGE₂ and PGI₂ by preadipocytes: (A) effects of selected concentrations of BmooMPα-I in the release of PGE₂ at 24 h; (B) time-course of BmooMPα-I-induced release of PGE₂; (C) time-course of BmooMPα-I-induced release of PGI₂. Preadipocytes were incubated with BmooMPα−I (0.06, 0.12, or 0.24 µM) or DMEM (control) for 1, 3, 6, 12, or 24 h. Concentrations of PGE₂ and PGI₂ in culture supernatants were determined by EIA. Results are expressed as means ± SEM of 3 experiments. Note: * p < 0.05 vs. control; ^# p < 0.05 vs. BmooMPα−I (two-way ANOVA and Bonferroni post-test).