AD |
Alzheimer’s disease |
ALS |
amyotrophic lateral sclerosis |
AMPA |
α-amino-3 hydroxy-5-methyl-4-isoxazolepropionic acid receptor |
AMPK |
adenosine monophosphate-activated protein kinase |
ANT |
adenine nucleotide translocase |
APAF-1 |
apoptosis protease-activating factor-1 |
ASC |
adaptor protein |
ATP |
adenosine triphosphate |
Aβ |
amyloid beta-peptide |
BAP31 |
B-cell receptor-associated protein 31 |
BDNF |
brain-derived neurotrophic factor |
BER |
Base excision repair |
β/cAMP |
β-adrenergic signalling |
Ca2+
|
Calcium |
CAMKII |
Ca2+/calmodulin-dependent protein kinase |
CAT |
Catalase |
CDKs |
cyclin-dependent kinases |
CICR |
Ca2+-induced Ca2+ release |
CHCHD2 |
coiled-coil-helix-coiled-coil-helix domain containing 2 |
CHCHD10 |
coiled-coil-helix-coiled-coil-helix domain-containing 10 |
CREB |
cAMP response element-binding protein |
Cybrid |
cytoplasmatic hybrids |
CypD |
cyclophilin D |
CytC |
cytochrome C |
Drp1 |
dynamin-related protein 1 |
EMRE |
essential MCU regulator |
eNOS |
endothelial NOS |
ER |
endoplasmic reticulum |
ERKs |
extracellular signal-regulated kinases |
Fis1 |
mitochondrial fission 1 |
FUS |
fused in sarcoma |
FZ |
frizzled receptor |
GABA |
γ-aminobutyric acid |
GPx |
glutathione peroxidase |
GSH |
Glutathione |
Grp75 |
mitochondrial chaperone glucose-regulated protein 75 |
GSK3β |
glycogen synthase kinase-3β |
H2O2
|
hydrogen peroxide |
HD |
Huntington’s disease |
HKII |
hexokinase II |
HTT |
Huntingtin |
IKK |
IkB kinase |
IL-18 |
interleukin 18 |
IL-1β |
interleukin 1β |
IL-6 |
interleukin 6 |
IMM |
inner mitochondrial membrane |
INF2 |
inverted formin 2 |
IP3R |
inositol triphosphate receptor |
IR |
insulin receptor |
IRS |
insulin receptor substrate |
JNK |
c-Jun N-terminal kinase |
LRP5/6 |
low-density lipoprotein receptor-related protein 5/6 |
LRRK |
Leucine Rich Repeat Kinase 2 |
LTP |
long-term potentiation |
MAM |
mitochondria associated membranes |
MAPK |
mitogen activated protein kinases |
MCI |
mild cognitive impairment |
MCU |
mitochondrial Ca2+ uniporter |
MCUb |
Mitochondrial Calcium Uniporter Dominant Negative Subunit Beta |
MCUR1 |
MCU regulator 1 |
MFF |
mitochondrial fission factor |
MFN |
Mitofusin |
MFN1 |
mitofusin protein 1 |
MFN2 |
mitofusin protein 2 |
MICU1 |
mitochondrial calcium uptake 1 |
MICU2 |
mitochondrial calcium uptake 2 |
MiD49 |
mitochondrial dynamic protein 49 |
MiD50 |
mitochondrial dynamic protein 50 |
Miro |
Mitochondrial Rho GTPase |
MNRR1 |
Mitochondria Nuclear Retrograde Regulator 1 |
mPTP |
mitochondrial permeability transition pore |
MPTP |
1-methyl4-phenyl-1,2,3,4-tetrahydropyridine |
MRC |
mitochondrial respiratory chain |
mtDNA |
mitochondrial DNA |
mtNOS |
mitochondrial NOS |
mTOR |
mechanistic target of rapamycin kinase |
Myo19 |
myosin19 |
NAD+/NADH |
nicotinamide adenine dinucleotide |
NCLX |
Li+-permeable Na+/Ca2+ exchanger |
NFAT |
nuclear factor of activated T-cells |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NLRP3 |
Nod-like receptor 3 |
NMDAR |
N-methyl-D-aspartate receptor |
nNOS |
neuronal NOS |
NO |
Nitric oxide |
NOS |
constitutive NO-synthase |
NRF1 |
nuclear respiratory factor 1 |
NRF2 |
nuclear respiratory factor 2 |
O2·−
|
superoxide anion |
OH.−
|
hydroxyl radical |
OMM |
outer mitochondrial membrane |
ONOO−
|
Peroxynitrite |
OPA1 |
protein optic atrophy 1 |
p38α |
p38 mitogen-activated protein kinase alpha |
PACS-2 |
phosphofurin acidic cluster sorting protein 2 |
PD |
Parkinson’s disease |
PGC-1α |
peroxisome proliferator-activated receptor-γ (PPARγ) coactivator-1α |
PGC1β |
peroxisome proliferator-activated receptor gamma coactivator 1-beta |
PI3K |
phospho-inositol-3 kinase |
PINK1 |
PTEN-induced kinase 1 |
PIP |
phosphatidylinositol phosphate |
PKC |
protein kinase C |
PRC |
PGC-related coactivator |
PS2 |
presenilin 2 |
pS302 |
phosphorylation of insulin receptor at serine-302 |
pS307 |
phosphorylation of insulin receptor at serine-307 |
PTPIP51 |
tyrosine phosphatase-interacting protein-51 |
ROS |
reactive oxygen species |
RyR |
ryanodine receptor |
SERCA |
sarco/endoplasmic reticulum Ca2+-ATPase |
SIRT |
silent mating type information regulation 2 homolog |
SOC |
store-operated Ca2+ channel |
SOCE |
store operated Ca2+ entry |
SOCS |
suppressor cytokine signalling |
SOD |
antioxidant enzymes superoxide dismutase |
SOD1 |
Cu/Zn superoxide dismutase 1 |
SLC25A23 |
solute carrier 25A23 |
STIM |
stromal interaction molecule |
T2D |
type 2 diabetes |
SNPC |
substantia nigra pars compacta |
SNPH |
Syntaphilin |
TCA |
tricarboxylic acid cycle |
TARDBP/TDP-43 |
transactive response DNA binding protein 43 |
TFAM |
mitochondrial transcription factor A |
TFB1M |
cofactor mitochondrial transcription factor B |
TH |
thyroid hormone |
TNF-α |
tumor necrosis factor α |
TOMM 40 |
Translocase of the OMM 40 |
TRAK |
trafficking kinesin protein |
TRP |
transient receptor potential |
VAPB |
vesicle-associated membrane protein-B |
VDAC |
voltage dependent anion channel 1 |
VGCC |
voltage-gated Ca2+ channels |
WISP3/CCN6 |
Wnt-induced signaling protein 3 |
Wnt |
Wnt signaling pathway |
ΔΨm |
mitochondrial membrane potential. |