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Proteins involved in mitochondrial dysfunction in Alzheimer’s disease.
| Molecule | Function | Ref. |
|---|---|---|
| Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) | MRC | [297] |
| ERK | Oxidative stress-mediated ERK signal | [298] |
| Amyloid beta (Aβ) binding alcohol dehydrogenase (ABAD) | Promotes Aβ-mediated mitochondrial a dysfunction | [299] |
| mtNADH dehydrogenase 1 (mt-Nd1) |
MRC | [300] |
| OPA1, Mfn1, Mfn2, DRP1 and Fis1 |
Mitochondrial fusion | [269] |
| MT-ND2 and MT-ND5 | MRC | [301] |
