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. 2021 Jul 16;11(7):1041. doi: 10.3390/biom11071041

Table 3.

Changes in inflammation indices concentration during the period of whole-body cryotherapy (WBC) treatment in the group of long-distance runners (RUN) and in the group of untrained men (UTR).

ANOVA
Variable WBC Total RUN UTR PA WBC PA × WBC
CRP T1 Mean ± SD 1.84 ± 1.93 2.12 ± 2.66 1.57 ± 0.79 F 0.02 0.83 0.94
(mg/L) ΔT2vsT1 Mean (95% CI) 0.70 (−0.74, 2.13) −0.12 (−2.23, 1.99) 1.51 (−0.70, 3.72) p 0.89 0.48 0.43
ΔT3vsT1 Mean (95% CI) −1.23 (0.97, 2.36) −0.59 (−2.53, 1.36) 0.33 (−1.07, 1.73) η2 <0.01 0.04 0.05
ΔT4vsT1 Mean (95% CI) −0.93 (1.11, 2.18) 0.06 (−2.01, 2.14) 0.12 (−0.79, 1.02) 1-β 0.05 0.22 0.24
IL-6 T1 Mean ± SD 1.76 ± 1.05 1.34 ± 0.98 2.18 ± 0.98 *,RUN F 17.72 1.39 0.70
(pg/mL) ΔT2vsT1 Mean (95% CI) −0.02 (−0.52, 0.49) −0.23 (−0.83, 0.37) 0.19 (−0.72, 1.11) p <0.01 0.26 0.56
ΔT3vsT1 Mean (95% CI) −0.06 (−0.60, 0.49) −0.20 (−0.88, 0.47) 0.09 (0.90, 1.08) η2 0.50 0.07 0.04
ΔT4vsT1 Mean (95% CI) −0.41 (−0.94, 0.12) −0.32 (−1.00, 0.36) −0.51 (−1.47, 0.45) 1-β 0.98 0.35 0.19
IL-1β T1 Mean ± SD 1.55 ± 0.62 1.60 ± 0.54 1.49 ± 0.71 F 5.39 0.10 0.46
(pg/mL) ΔT2vsT1 Mean (95% CI) −0.08 (−0.45, 0.28) −0.03 (−0.62, 0.96) −0.13 (−0.68, 0.42) p 0.03 0.96 0.71
ΔT3vsT1 Mean (95% CI) 0.01 (−0.43, 0.45) 0.17 (−0.62, 0.96) −0.15 (−0.69, 0.39) η2 0.23 0.01 0.03
ΔT4vsT1 Mean (95% CI) −0.02 (−0.46, 0.42) 0.16 (−0.67, 0.98) −0.20 (−0.69, 0.30) 1-β 0.59 0.07 0.14
IL-10 T1 Mean ± SD 4.13 ± 1.79 4.30 ± 1.34 3.96 ± 2.21 F 0.13 2.24 0.06
(pg/mL) ΔT2vsT1 Mean (95% CI) −0.92 (−1.95, 0.12) −1.11 (−2.75, 0.54) −0.73 (−2.32, 0.87) p 0.72 0.09 0.98
ΔT3vsT1 Mean (95% CI) −1.02 (−2.14, 0.10) −1.14 (−2.64, 0.36) −0.90 (−2.88, 1.08) η2 0.01 0.11 <0.01
ΔT4vsT1 Mean (95% CI) 0.04 (−1.56, 1.64) 0.04 (−1.87, 1.96) 0.04 (−2.96, 3.03) 1-β 0.06 0.54 0.06

SD: standard deviation, CI: confidence interval, T1: measurement before 1 WBC, T2: measurement after 12 WBC, T3: measurement after 24 WBC, T4: measurement 7 days after completing WBC treatments, ΔvsT1: difference in results for points T2, T3 and T4 vs. T1; CRP: C-reactive protein, IL-6: interleukin 6, IL-1β: interleukin 1β, IL-10: interleukin 10; * statistically significant difference (p < 0.05), η2: partial eta squared (0.010–0.059 = small clinical effect, 0.060–0.139 = moderate clinical effect, ≥ 0.14 = large clinical effect), 1-β: power of statistical test.