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. 2021 Jul 16;11(7):1042. doi: 10.3390/biom11071042

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Location information of methylation sites related to EGFR inhibitor response. (A) The proportion of predicted methylation sites located in enhancer, promoter, or TF binding regions. (B) The light blue bar represents the number of responsive genes supported by evidence; that is, the methylation sites closely associated with the responsive genes were located in important regulatory regions (enhancer, promoter, transcription factor binding) for each of the 10 EGFR inhibitors, respectively.