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. Author manuscript; available in PMC: 2021 Jul 23.
Published in final edited form as: Int J Head Neck Surg. 2019 Jul-Sep;10(3):57–61. doi: 10.5005/jp-journals-10001-1373

Flowchart 1: Proposed mechanisms by which OSA impairs cognition.

Flowchart 1:

OSA, obstructive sleep apnea; ASCVD, atherosclerotic cardiovascular disease; SA, sympathomimetic activation; INF, inflammation; BA, beta amyloid accumulation; OS, oxidative stress; ED, endothelial dysfunction; MD, myelin decrease; NE, neural excitability, reduced; TAU, Tau hyperphosphorylation