Table 2.
Comparison of Bone Tissue Characteristics (Total Bone Area) From Melorheostotic Lesions Versus Unaffected Bone
| Bone sample | Unaffected (n = 6) | Affected (n = 8)a | p Value |
|---|---|---|---|
| BMDD parameters | |||
| CaMean (weight % calcium) | 23.23 (1.20) | 22.17 (0.49) | 0.035* |
| CaPeak (weight % calcium) | 24.02 (1.23) | 23.70 (0.39) | 0.43 (ns) |
| CaWidth (Δ weight % calcium) | 4.31 (0.66) | 4.87 (0.68) | 0.15 (ns) |
| CaLow (% bone area) | 4.87 (2.07) | 9.11 (2.52) | 0.009** |
| CaHigh (% bone area) | 26.03 (19.37) | 15.55 (4.02) | 0.11 (ns) |
| OLS parameters | |||
| OLS-density (number OLS/mm2) | 216.3 (70.34) | 277.9 (35.73) | 0.050 |
| OLS-porosity (%) | 0.572 (0.15) | 0.797 (0.06) | 0.013* |
| OLS-area (μm2) | 27.04 (1.75) | 29.07 (1.74) | 0.03* |
| OLS-perimeter (μm) | 17.76 (1.08) | 17.78 (1.82) | 0.93 |
| OLS-aspect ratio | 2.62 (0.41) | 2.55 (0.27) | 0.71 |
BMDD = bone mineralization density distribution; OLS = osteocyte lacunae sections.
Values are given as mean (±SD).
a
For Melo 4 and Melo 18, two affected samples were available and evaluated separately.
*
p ≤ 0.05
**
p < 0.01
****
p < 0.0001 (results from paired t test).