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. 2021 Jul 9;11:630675. doi: 10.3389/fonc.2021.630675

Table 3.

Clinicopathological characteristics of early cases of three pathological types.

DC (n = 335) UDC (n = 210) SRCC (n = 60) P
Sex
  Male 235 (70.1%) 105 (50%) 34 (56.7%)
  Female 100 (29.9%) 105 (50%) 26 (43.3%) <0.001
Age (years)
 <65 204 (60.9%) 161 (76.7%) 46 (76.7%)
  ≥65 131 (39.1%) 49 (23.3%) 14 (23.3%) <0.001
Tumor size (cm)
 ≤2 198 (59.1%) 148 (70.5%) 46 (76.7%)
 >2 137 (40.9%) 62 (29.5%) 14 (23.3%) 0.003
Macroscopic type
 I 20 (6.0%) 0 (0%) 0 (0%)
 IIa 14 (4.2%) 6 (2.9%) 1 (1.7%)
 IIb 36 (10.7%) 20 (9.5%) 20 (33.3%)
 IIc 175 (52.2%) 123 (58.6%) 30 (50.0%)
 III 85 (25.4%) 61 (29.0%) 8 (13.3%)
 IIa+IIb 1 (0.3%) 0 (0%) 0 (0%)
 IIa+IIc 3 (0.9%) 0 (0%) 1 (1.7%)
 IIb+IIc 1 (0.3%) 0 (0%) 0 (0%) <0.001
Pure/mixed
 Pure 167 (49.9%) 81 (38.6%) 43 (71.7%)
 Mixed 168 (50.1%) 129 (61.4%) 17 (28.3%) <0.001
Infiltration depth
 Intramucosal 134 (40.0%) 89 (42.4%) 46 (76.7%)
 Submucosal 191 (57.0%) 115 (54.8%) 14 (23.3%) <0.001
 Excluded 10 (3.0%) 6 (2.8%) 0
LNM
 + 54 (16.1%) 49 (23.3%) 6 (10%)
 - 281 (83.9%) 161 (76.7%) 54 (90%) 0.024

DC, differentiated carcinoma; UDC, undifferentiated carcinoma; SRCC, signet ring cell carcinoma.