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. 2021 Jul 9;11:630675. doi: 10.3389/fonc.2021.630675

Table 6.

Univariate and multivariate analyses of the risk factors for lymph node metastasis in early undifferentiated gastric cancer.

Risk factor Univariate analysis (n = 270) Multivariate analysis (n = 270)
n LNM (+) P P OR 95%CI
Sex
  Male 139 25 (18.0%)
  Female 131 30 (22.9%) 0.316
Age (years)
 <65 207 44 (21.3%)
  ≥65 63 11 (17.5%) 0.512
Tumor size (cm) 0.005 2.519 1.313-4.829
 ≤2 194 28 (14.4%)
 >2 76 27 (35.5%) <0.001
Infiltration depth <0.001 3.993 1.920-8.305
 Intramucosal 135 12 (8.9%)
  Submucosal 129 42 (32.6%) <0.001
  Excluded 6 1 (16.7%)
Pathological type 0.617 1.225 0.553-2.712
 SRCC 60 6 (10.0%)
 PDC 204 49 (24.0%)
 MGC 6 0 (0%) 0.027
Pure/mixed
 Pure 124 24 (19.4%)
 Mixed 146 31 (21.2%) 0.703
Total 270 55 (20.4%)

MGC, mucinous carcinoma; PDC, poorly differentiated carcinoma; SRCC, signet ring cell carcinoma.