Table 3.

Topological parameters of the top 10 hub genes of the E-H network ranked by degree.

Gene symbol	Betweenness Centrality	Closeness Centrality	Clustering Coefficient	Topological Coefficient	Degree
AKT1	0.206016	0.761194	0.258824	0.240336	35
EGFR	0.089246	0.69863	0.337438	0.270453	29
ESR1	0.067784	0.68	0.39886	0.292665	27
PTGS2	0.085964	0.662338	0.346667	0.276078	25
AR	0.041309	0.62963	0.424242	0.313636	22
MMP9	0.040523	0.607143	0.45614	0.308421	19
RELA	0.027075	0.6	0.450292	0.330827	19
ABCG2	0.028045	0.579545	0.433333	0.306122	16
AHR	0.048945	0.593023	0.55	0.34	16
CYP3A4	0.038392	0.566667	0.358333	0.271277	16