Table 1.
Diagnosis | n | Age | Sex | Handedness | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Median | Range | Male | Female | R | L | |||||||||
A-T | 15 | 10 | 6–18 | 9 | 6 | 14 | 1 | |||||||
Control | 15 | 11 | 4–5 | 9 | 6 | 14 | 1 | |||||||
BARS | ||||||||||||||
Age group | A-T participant | Left arm (0–4) | Right arm (0–4) | Left leg (0–4) | Right leg (0–4) | Gait (0–8) | Oculomotor (0–4) | Dysarthria (0–4) | Scaled total (0–36) | Clinical phenotype | Hyperkinetic movements (tics, chorea, myoclonus, ballismus, arrhythmic adventitious movements) | Tremor/rhythmic movements | ||
Limbs | Face, head, trunk | Limbs | Face, head, trunk | |||||||||||
Middle childhood (6–11y) | 1 | 2 | 2 | 2.5 | 2.5 | 2.5 | 1 | – | 14.4 | Classic | Y | Y | N | N |
2 | 1 | 1 | 2.5 | 2.5 | 3 | 1 | 2 | 13 | Classic | Y | Y | N | N | |
3 | 0.5 | 0.5 | 2.5 | 2.5 | 2.5 | 1 | – | 11.0 | Classic | N | N | N | N | |
4 | 3 | 2.5 | 2.5 | 2.5 | 7 | 1 | 3.5 | 22 | Classic | Y | Y | N | N | |
5 | 3 | 2 | 3.5 | 3.5 | 6.5 | 1.5 | 3 | 23 | Classic | Y | Y | Y | N | |
6 | 1.5 | 1 | 2.5 | 1.5 | 2.5 | 1 | 2 | 12 | Classic | Y | Y | N | N | |
7 | 3 | 2.5 | 3 | 2.5 | 7 | 1.5 | 3 | 22.5 | Classic | Y | Y | N | N | |
8 | 3 | 2.5 | 2.5 | 2.5 | 4.5 | 1 | 2.5 | 18.5 | Classic | Y | Y | N | N | |
9 | 3 | 2.5 | 2.5 | – | 6 | 1 | 3 | 20.8 | Classic | Y | Y | N | N | |
Early adolescence (12–18y) | 10 | 3 | 3 | 2.5 | 3 | 6.5 | 2 | 3 | 23 | Classic | Y | Y | N | N |
11 | 2.5 | 2.5 | 3.5 | 3 | 5 | 1 | 2.5 | 20 | Classic | Y | Y | N | N | |
12 | 2 | 2 | 2.5 | 2.5 | 4 | 1 | 2 | 16 | Classic | Y | Y | N | Y | |
13 | 2 | 2 | 2 | 2 | 7 | 1 | 2 | 18 | Classic | Y | Y | Y | N | |
14 | 3.5 | 3 | 3.5 | 3.5 | 7 | 1.5 | 2.5 | 24.5 | Classic | Y | Y | Y | Y | |
15 | 3 | 2.5 | 4 | 4 | 8 | 1 | 3 | 25.5 | Classic | Y | Y | N | N |