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GABABR modulators do not affect mean mEPSC or mIPSC amplitudes
| Control | Baclofen | CGP55845 | ANOVA | |
|---|---|---|---|---|
| mEPSC (pA) | ||||
| WT |
7.5 ± 0.3 n = 14 |
7.3 ± 0.4 n = 7 |
7.3 ± 0.3 n = 8 |
F = 0.18 p = 0.84 |
| Tsc2+/- |
7.7 ± 0.4 n = 14 |
7.2 ± 0.9 n = 7 |
7.2 ± 0.4 n = 7 |
F = 0.47 p = 0.63 |
| mIPSC (pA) | ||||
| WT |
9.6 ± 0.5 n = 14 |
9.2 ± 0.9 n = 7 |
9.4 ± 0.8 n = 8 |
F = 0.11 p = 0.89 |
| Tsc2+/- |
9.2 ± 0.9 n = 14 |
9.6 ± 1.2 n = 7 |
9.2 ± 1.1 n = 7 |
F = 0.05 p = 0.96 |
